7N06

SARS-CoV-2 Nsp15 endoribonuclease post-cleavage state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Uridylate-specific endoribonuclease	polymer	378	42525.3	6	UniProt (P0DTD1) Pfam (PF19219) Pfam (PF19216) Pfam (PF19215) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)	NendoU,Non-structural protein 15,nsp15
2	G, H, I, J, K...	RNA (5'-R(*AP*UP*A)-3')	polymer	3	919.6	6		Homo sapiens
3		water	water		18.0	555	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 2 - 346 (UniProt: P0DTD1)

PDB	External Database	Details
Met -31	-	initiating methionine
Gly -30	-	expression tag
Ser -29	-	expression tag
Ser -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
Ser -21	-	expression tag
Ser -20	-	expression tag
Gly -19	-	expression tag
Leu -18	-	expression tag
Val -17	-	expression tag
Pro -16	-	expression tag
Arg -15	-	expression tag
Gly -14	-	expression tag
Ser -13	-	expression tag
His -12	-	expression tag
Met -11	-	expression tag
Leu -10	-	expression tag
Glu -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Leu -1	-	expression tag
Glu 0	-	expression tag
Met 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	260669.5
All*	Total formula weight	260669.5

*Water molecules are not included.