7MYD

Leishmania major dihydroorotate dehydrogenase in complex with 5-amino-2-(1H-pyrrol-1-yl)benzonitrile

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (AAA, BBB)	Dihydroorotate dehydrogenase (fumarate)	polymer	354	38245.6	2	UniProt (Q4QEW7) Pfam (PF01180)	Leishmania major	Dihydroorotate oxidase
2	C, I (AAA, BBB)	FLAVIN MONONUCLEOTIDE	non-polymer		456.3	2	Chemie (FMN)
3	D, E, J (AAA, BBB)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4	F, G, K (AAA, BBB)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5	H (AAA)	5-azanyl-2-pyrrol-1-yl-benzenecarbonitrile	non-polymer		183.2	1	Chemie (SNQ)
6	L, M (AAA, BBB)	water	water		18.0	334	Chemie (HOH)

Sequence modifications

AAA, BBB: 1 - 320 (UniProt: Q4QEW7)

PDB	External Database	Details
Met -33	-	expression tag
Gly -32	-	expression tag
Ser -31	-	expression tag
Ser -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
Ser -23	-	expression tag
Ser -22	-	expression tag
Gly -21	-	expression tag
Leu -20	-	expression tag
Val -19	-	expression tag
Pro -18	-	expression tag
Arg -17	-	expression tag
Gly -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
Met -13	-	expression tag
Ala -12	-	expression tag
Ser -11	-	expression tag
Met -10	-	expression tag
Thr -9	-	expression tag
Gly -8	-	expression tag
Gly -7	-	expression tag
Gln -6	-	expression tag
Gln -5	-	expression tag
Met -4	-	expression tag
Gly -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76491.3
Non-Polymers*	Number of molecules	9
	Total formula weight	1660.4
All*	Total formula weight	78151.7

*Water molecules are not included.