7MXQ
Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (r-1)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | Z | Exonuclease 1 | polymer | 358 | 40354.8 | 1 | UniProt (Q9UQ84) Pfam (PF00752) Pfam (PF00867) In PDB | Homo sapiens (Human) | hExo1, Exonuclease I, hExoI |
2 | A | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3') | polymer | 13 | 3951.6 | 1 | synthetic construct | ||
3 | B | DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3') | polymer | 10 | 3045.0 | 1 | synthetic construct | ||
4 | Z, B | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
5 | Z | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
6 | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
Z: 1 - 352 (UniProt: Q9UQ84)
PDB | External Database | Details |
---|---|---|
Glu 353 | - | expression tag |
Asn 354 | - | expression tag |
Leu 355 | - | expression tag |
Tyr 356 | - | expression tag |
Phe 357 | - | expression tag |
Gln 358 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 47351.4 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 132.9 | |
All* | Total formula weight | 47484.2 |