7MXH

CD1c with antigen analogue 3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	T-cell surface glycoprotein CD1c/T-cell surface glycoprotein CD1b chimeric protein	polymer	285	31957.7	1	UniProt (P29017) UniProt (P29016) Pfam (PF16497) Pfam (PF07654) In PDB	Homo sapiens (Human)
2	B	Beta-2-microglobulin	polymer	108	12616.1	1	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (Human)
3	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
4	A	2,6-anhydro-1-deoxy-1,1-difluoro-1-[(R)-hydroxy{[(4S,8S,12S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-D-glycero-D-galacto-heptitol	non-polymer		743.0	1	Chemie (ZQ7)
5	A	DODECANE	non-polymer		170.3	1	Chemie (D12)
6	A	(2S)-2,3-dihydroxypropyl hexadecanoate	non-polymer		330.5	1	Chemie (ZP7)
7	A, B	MALONIC ACID	non-polymer		104.1	2	Chemie (MLA)
8		water	water		18.0	121	Chemie (HOH)

Sequence modifications

A: 1 - 194 (UniProt: P29017)

PDB	External Database	Details
Ser 5	Gln 23	conflict
Gln 52	Asn 70	engineered mutation
Gln 57	Asn 75	engineered mutation
Gly 108	Lys 126	engineered mutation
Gln 128	Asn 146	engineered mutation

A: 195 - 279 (UniProt: P29016)

PDB	External Database	Details
Gly 242	Trp 259	engineered mutation
Gly 280	-	expression tag
Ser 281	-	expression tag
Leu 282	-	expression tag
Val 283	-	expression tag
Pro 284	-	expression tag
Arg 285	-	expression tag

B: 1 - 100 (UniProt: P61769)

PDB	External Database	Details
Asp -1	-	expression tag
Ala 0	-	expression tag
Gly 101	-	expression tag
Ser 102	-	expression tag
Leu 103	-	expression tag
Val 104	-	expression tag
Pro 105	-	expression tag
Arg 106	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	44573.9
Non-Polymers*	Number of molecules	6
	Total formula weight	1673.2
All*	Total formula weight	46247.0

*Water molecules are not included.