7MWX
Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2 with tamarin CD81
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C, G | Core protein precursor eE2 | polymer | 259 | 29314.1 | 2 | UniProt (A0A2I6PIY1) Pfam (PF01560) UniProt (by SIFTS) (A0A2I6PIY9) In PDB | Hepacivirus C | Envelope glycoprotein E1,Envelope glycoprotein E2,Genome polyprotein,Gp32,Hepacivirin,Mature core protein,NS1,NS3 helicase,NS3 protease,NS3P,NS5B,Non-structural protein 4A,Non-structural protein 4B,Non-structural protein 5A,Protease NS2,RNA-directed RNA polymerase,Serine protease/helicase NS3,Viroporin p7,Viroporin p70,gp35,gp68,gp70,p21,p23,p27,p56/58,p68,p8 |
2 | A, E | 2A12 Fab Heavy Chain | polymer | 218 | 23207.6 | 2 | Mus musculus | ||
3 | B, F | 2A12 Fab Light Chain | polymer | 218 | 24111.6 | 2 | Mus musculus | ||
4 | D, H | CD81 protein | polymer | 93 | 10141.4 | 2 | UniProt (Q9N0J9) Pfam (PF00335) In PDB | Saguinus oedipus (Cotton-top tamarin) | |
5 | I | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
6 | J | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
7 | C, G | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
D, H: 10 - 99 (UniProt: Q9N0J9)
PDB | External Database | Details |
---|---|---|
Thr 7 | - | cloning artifact |
Gly 8 | - | cloning artifact |
Ser 9 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 173549.4 | |
Branched | Number of molecules | 2 |
Total formula weight | 1010.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 663.6 | |
All* | Total formula weight | 175224.0 |