7MVV

Single particle cryo-EM structure of the Chaetomium thermophilum Nup192-Nic96-Nup53-Nup145N complex (Nup192 residues 1-1756; Nic96 residues 240-301; Nup53 31-67; Nup145N 616-683)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Nucleoporin NUP192	polymer	1784	200047.5	1	UniProt (G0S4T0) Pfam (PF11894)	Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)	Nuclear pore protein NUP192
2	B (B)	Nucleoporin NIC96	polymer	63	7173.9	1	UniProt (G0S024)	Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)	Nuclear pore protein NIC96
3	C (D)	Nucleoporin NUP53	polymer	38	4173.6	1	UniProt (G0S156)	Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)	Nuclear pore protein NUP53
4	D (C)	Nucleoporin NUP145N	polymer	69	7078.0	1	UniProt (G0SAK3)	Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)	N-NUP145

Sequence modifications

A: 1 - 1756 (UniProt: G0S4T0)

PDB	External Database	Details
Gly -27	-	expression tag
Pro -26	-	expression tag
Leu -25	-	expression tag
Met -24	-	expression tag
Ser -23	-	expression tag
Gly -22	-	expression tag
Leu -21	-	expression tag
Asn -20	-	expression tag
Asp -19	-	expression tag
Ile -18	-	expression tag
Phe -17	-	expression tag
Glu -16	-	expression tag
Ala -15	-	expression tag
Gln -14	-	expression tag
Lys -13	-	expression tag
Ile -12	-	expression tag
Glu -11	-	expression tag
Trp -10	-	expression tag
His -9	-	expression tag
Glu -8	-	expression tag
Gly -7	-	expression tag
Ser -6	-	expression tag
Ala -5	-	expression tag
Gly -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag

B: 240 - 301 (UniProt: G0S024)

PDB	External Database	Details
Ser 239	-	expression tag

D: 31 - 67 (UniProt: G0S156)

PDB	External Database	Details
Ser 30	-	expression tag

C: 616 - 683 (UniProt: G0SAK3)

PDB	External Database	Details
Ser 615	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	218473.0
All*	Total formula weight	218473.0

*Water molecules are not included.