7MTQ
CryoEM Structure of Full-Length mGlu2 in Inactive-State Bound to Antagonist LY341495
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Metabotropic glutamate receptor 2 | polymer | 855 | 93932.4 | 2 | UniProt (Q14416) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003) | Homo sapiens (Human) | mGluR2 |
| 2 | C, F (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 3 | D, E (A, B) | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine | non-polymer | 353.4 | 2 | Chemie (Z99) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 187864.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1149.2 | |
| All* | Total formula weight | 189014.0 |
