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7MTQ

CryoEM Structure of Full-Length mGlu2 in Inactive-State Bound to Antagonist LY341495

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BMetabotropic glutamate receptor 2polymer85593932.42UniProt (Q14416)
Pfam (PF01094)
Pfam (PF07562)
Pfam (PF00003)
In PDB
Homo sapiens (Human)mGluR2
2A, B2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
3A, B2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alaninenon-polymer353.42Chemie (Z99)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight187864.9
Non-Polymers*Number of molecules4
Total formula weight1149.2
All*Total formula weight189014.0
*Water molecules are not included.

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PDB entries from 2024-07-24

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