7MTQ
CryoEM Structure of Full-Length mGlu2 in Inactive-State Bound to Antagonist LY341495
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Metabotropic glutamate receptor 2 | polymer | 855 | 93932.4 | 2 | UniProt (Q14416) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003) | Homo sapiens (Human) | mGluR2 |
| 2 | C, F (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 3 | D, E (A, B) | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine | non-polymer | 353.4 | 2 | Chemie (Z99) PubChem (44300270) PubChem (44348804) PubChem (57824323) PubChem (69351741) PubChem (68198047) PubChem (4364840) PubChem (89651894) PubChem (6604829) PubChem (9819927) PubChem (9975366) PubChem (10618042) PubChem (10713043) PubChem (10807972) PubChem (138113521) PubChem (156758060) PubChem (163320174) PubChem (169545577) PubChem (171041419) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 187864.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1149.2 | |
| All* | Total formula weight | 189014.0 |
