7MSB
Structure of EED bound to EEDi-4259
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Polycomb protein EED | polymer | 368 | 42412.2 | 1 | UniProt (O75530) Pfam (PF00400) In PDB | Homo sapiens (Human) | hEED,Embryonic ectoderm development protein,WD protein associating with integrin cytoplasmic tails 1,WAIT-1 |
2 | A | (9aM,12aS)-12-{[(5-fluoro-1-benzofuran-4-yl)methyl]amino}-7-(trifluoromethyl)-4,5-dihydro-3H-2,4,11,12a-tetraazabenzo[4,5]cycloocta[1,2,3-cd]inden-3-one | non-polymer | 481.4 | 1 | Chemie (ZNG) | |||
3 | water | water | 18.0 | 417 | Chemie (HOH) |
Sequence modifications
A: 77 - 441 (UniProt: O75530)
PDB | External Database | Details |
---|---|---|
Ser 74 | - | expression tag |
Asn 75 | - | expression tag |
Ala 76 | - | expression tag |
Thr 370 | Met 370 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42412.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 481.4 | |
All* | Total formula weight | 42893.6 |