7MOZ
Structure of HDAC2 in complex with a macrocyclic inhibitor (compound 25)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Histone deacetylase 2 | polymer | 376 | 43062.0 | 3 | UniProt (Q92769) Pfam (PF00850) | Homo sapiens (Human) | HD2 |
| 2 | D, O, W (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | AA, E, F, G, H... (C, A, B) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 4 | BA, CA, I, J, R... (C, A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 5 | DA, EA, K, L, M... (C, A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 7 | Chemie (PEG) | |||
| 6 | FA, N, V (C, A, B) | (1R,3S,6S,18R,27R)-6-(6,6-dihydroxyoctyl)-5,8,18,27,34-pentaazahexacyclo[25.2.2.1~7,10~.1~11,15~.1~14,18~.0~1,3~]tetratriaconta-7,9,11(33),12,14,16-hexaene-4,32-dione (non-preferred name) | non-polymer | 632.9 | 3 | Chemie (ZL4) | |||
| 7 | GA, HA, IA (A, B, C) | water | water | 18.0 | 1160 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 129186.0 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 4038.7 | |
| All* | Total formula weight | 133224.7 |
