7MOS
Structure of HDAC2 in complex with a macrocyclic inhibitor (compound 4)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Histone deacetylase 2 | polymer | 376 | 43062.0 | 3 | UniProt (Q92769) Pfam (PF00850) | Homo sapiens (Human) | HD2 |
| 2 | D, P, Z (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | AA, BA, CA, DA, E... (C, A, B) | SULFATE ION | non-polymer | 96.1 | 13 | Chemie (SO4) | |||
| 4 | EA, FA, J, K, U... (C, A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 5 | GA, HA, L, M, N... (C, A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 7 | Chemie (PEG) | |||
| 6 | IA, O, Y (C, A, B) | (3S,18S,20aR)-18-(6,6-dihydroxyoctyl)-1,5,6,7,8,18,19,20a-octahydro-4H-14,17-epiminoazeto[1,2-g][1,7,10,13]benzoxatriazacycloheptadecin-20(2H)-one | non-polymer | 484.6 | 3 | Chemie (ZLV) | |||
| 7 | JA, KA, LA (A, B, C) | water | water | 18.0 | 1078 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 129186.0 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 3882.2 | |
| All* | Total formula weight | 133068.2 |
