7MOH
Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with 5-diphosphoinositol 1,3,4,6-tetrakisphosphate (5PP-InsP4) and phosphate in conformation B (Pi(B))
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosine-protein phosphatase DSP1 | polymer | 171 | 19642.8 | 2 | UniProt (Q9ZVN4) Pfam (PF03162) | Arabidopsis thaliana (Mouse-ear cress) | Protein PLANT AND FUNGI ATYPICAL DUAL-SPECIFICITY PHOSPHATASE 1,AtPFA-DSP1,Tyrosine-protein phosphatase At1g05000 |
| 2 | C, D (A, B) | (1r,2R,3S,4r,5R,6S)-4-hydroxy-2,3,5,6-tetrakis(phosphonooxy)cyclohexyl trihydrogen diphosphate | non-polymer | 660.0 | 2 | Chemie (U6J) | |||
| 3 | E (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A, B: 49 - 215 (UniProt: Q9ZVN4)
| PDB | External Database | Details |
|---|---|---|
| Gly 45 | - | expression tag |
| Ser 46 | - | expression tag |
| Phe 47 | - | expression tag |
| Thr 48 | - | expression tag |
| Ser 150 | Cys 150 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 39285.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1415.0 | |
| All* | Total formula weight | 40700.6 |
