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7MOG

Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with 5-PCF2 Am-InsP5, an analogue of 5-InsP7

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Tyrosine-protein phosphatase DSP1polymer17119642.82UniProt (Q9ZVN4)
Pfam (PF03162)
Arabidopsis thaliana (Mouse-ear cress)Protein PLANT AND FUNGI ATYPICAL DUAL-SPECIFICITY PHOSPHATASE 1,AtPFA-DSP1,Tyrosine-protein phosphatase At1g05000
2C, D
(A, B)
(1,1-difluoro-2-oxo-2-{[(1s,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]amino}ethyl)phosphonic acidnon-polymer737.12Chemie (KDJ)
3E, F
(A, B)
waterwater18.0293Chemie (HOH)
Sequence modifications
A, B: 49 - 215 (UniProt: Q9ZVN4)
PDBExternal DatabaseDetails
Gly 45-expression tag
Ser 46-expression tag
Phe 47-expression tag
Thr 48-expression tag
Ser 150Cys 150engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight39285.5
Non-Polymers*Number of molecules2
Total formula weight1474.1
All*Total formula weight40759.7
*Water molecules are not included.

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PDB entries from 2024-10-30

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