7MO7
Cryo-EM structure of 2:2 c-MET/HGF holo-complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (D, A) | Hepatocyte growth factor | polymer | 728 | 83249.8 | 2 | UniProt (P14210) Pfam (PF00024) Pfam (PF00051) Pfam (PF00089) | Homo sapiens (Human) | Hepatopoietin-A,Scatter factor,SF |
| 2 | B, D (E, B) | Hepatocyte growth factor receptor | polymer | 1390 | 155720.6 | 2 | UniProt (P08581) Pfam (PF01833) Pfam (PF07714) Pfam (PF01403) Pfam (PF01437) | Homo sapiens (Human) | HGF receptor,HGF/SF receptor,Proto-oncogene c-Met,Scatter factor receptor,SF receptor,Tyrosine-protein kinase Met |
| 3 | E (F) | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose | branched | 1750.4 | 1 | In PDB GlyTouCan (G30141AL) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 477940.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1750.4 | |
| All* | Total formula weight | 479691.3 |
