7MNY

Crystal Structure of Nup358/RanBP2 Ran-binding domain 3 in complex with Ran-GPPNHP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I...	GTP-binding nuclear protein Ran	polymer	217	24543.2	6	UniProt (P62826) Pfam (PF00071) In PDB	Homo sapiens (Human)	Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein
2	B, D, F, H, J...	E3 SUMO-protein ligase RanBP2	polymer	141	16308.6	6	UniProt (P49792) Pfam (PF00638) In PDB	Homo sapiens (Human)	358 kDa nucleoporin,Nuclear pore complex protein Nup358,Nucleoporin Nup358,Ran-binding protein 2,RanBP2,p270
3	A, C, E, G, I...	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	non-polymer		522.2	6	Chemie (GNP)
4	A, C, E, G, I...	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
5		water	water		18.0	267	Chemie (HOH)

Sequence modifications

A, C, E, G, I, K: 1 - 216 (UniProt: P62826)

PDB	External Database	Details
Ser 0	-	expression tag

B, D, F, H, J, L: 2307 - 2441 (UniProt: P49792)

PDB	External Database	Details
Gly 2303	-	expression tag
Pro 2304	-	expression tag
Gly 2305	-	expression tag
Ser 2306	-	expression tag
Ala 2442	-	expression tag
Ala 2443	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	245110.5
Non-Polymers*	Number of molecules	12
	Total formula weight	3279.0
All*	Total formula weight	248389.5

*Water molecules are not included.