7MMN

Crystal Structure of the Prefusion RSV F Glycoprotein bound by human antibody AM14

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	L, E, G	AM14 Fab Light Chain	polymer	219	24029.7	3		Homo sapiens
2	A, C, J	Fusion glycoprotein F2	polymer	72	8173.3	3	UniProt (P03420) In PDB	Human respiratory syncytial virus
3	B, I, K	Fusion glycoprotein F1,Fibritin	polymer	414	45609.1	3	UniProt (P03420) Pfam (PF00523) In PDB	Human respiratory syncytial virus
4	M, H, D	AM14 Fab Heavy Chain	polymer	244	26380.4	3		Homo sapiens
5	B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
6	M	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)

Sequence modifications

B, I, K: 137 - 513 (UniProt: P03420)

PDB	External Database	Details
Cys 155	Ser 155	engineered mutation
Phe 190	Ser 190	engineered mutation
Leu 207	Val 207	engineered mutation
Cys 290	Ser 290	engineered mutation
Val 379	Ile 379	variant
Val 447	Met 447	variant

B, I, K: 514 - 550 (PDB: 7MMN)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	312577.6
Non-Polymers*	Number of molecules	2
	Total formula weight	313.3
All*	Total formula weight	312890.9

*Water molecules are not included.