7MLA

Solution NMR structure of HDMX in complex with Zn and MCo-52-2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Protein Mdm4	polymer	70	7797.3	1	UniProt (O15151) Pfam (PF13920) In PDB	Homo sapiens (Human)	Double minute 4 protein,Mdm2-like p53-binding protein,Protein Mdmx,p53-binding protein Mdm4
2	B	MCo-52-2	polymer	34	3598.0	1		synthetic construct
3	A	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A: 428 - 490 (UniProt: O15151)

PDB	External Database	Details
Gly 421	-	expression tag
Ser 422	-	expression tag
His 423	-	expression tag
Met 424	-	expression tag
Tyr 425	-	expression tag
Ser 426	-	expression tag
Gly 427	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	11395.3
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	11526.2

*Water molecules are not included.