7MLA
Solution NMR structure of HDMX in complex with Zn and MCo-52-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein Mdm4 | polymer | 70 | 7797.3 | 1 | UniProt (O15151) Pfam (PF13920) | Homo sapiens (Human) | Double minute 4 protein,Mdm2-like p53-binding protein,Protein Mdmx,p53-binding protein Mdm4 |
| 2 | B (B) | MCo-52-2 | polymer | 34 | 3598.0 | 1 | synthetic construct | ||
| 3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A: 428 - 490 (UniProt: O15151)
| PDB | External Database | Details |
|---|---|---|
| Gly 421 | - | expression tag |
| Ser 422 | - | expression tag |
| His 423 | - | expression tag |
| Met 424 | - | expression tag |
| Tyr 425 | - | expression tag |
| Ser 426 | - | expression tag |
| Gly 427 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 11395.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 11526.2 |
