7MKO

Escherichia coli RNA polymerase elongation complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	DNA-directed RNA polymerase subunit alpha	polymer	237	26213.8	2	UniProt (A0A4S5AL01) Pfam (PF01193) Pfam (PF01000) UniProt (by SIFTS) (P0A7Z4) In PDB	Escherichia coli (strain K12)	RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
2	C	DNA-directed RNA polymerase subunit beta	polymer	1340	150590.5	1	UniProt (A0A4S4NK82) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) UniProt (by SIFTS) (P0A8V2) In PDB	Escherichia coli (strain K12)	RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
3	D	DNA-directed RNA polymerase subunit beta'	polymer	1363	150865.8	1	UniProt (A0A6D2WUT6) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) UniProt (by SIFTS) (P0A8T7) In PDB	Escherichia coli (strain K12)	RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta'
4	E	DNA-directed RNA polymerase subunit omega	polymer	91	10249.5	1	UniProt (P0A800) Pfam (PF01192) In PDB	Escherichia coli (strain K12)	RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega
5	N	DNA (29-MER)	polymer	29	8840.7	1		Escherichia coli K-12
6	R	RNA (20-MER)	polymer	11	3625.2	1		Escherichia coli K-12
7	T	DNA (29-MER)	polymer	29	8813.6	1		Escherichia coli K-12
8	D	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
9	D	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
10	D	5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine	non-polymer		481.2	1	Chemie (2TM)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	385413.1
Non-Polymers*	Number of molecules	4
	Total formula weight	636.3
All*	Total formula weight	386049.4

*Water molecules are not included.