7MI6
Yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound, Model 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Fusion protein of Dynein and Endolysin | polymer | 2661 | 304889.9 | 1 | UniProt (P36022) UniProt (P00720) Pfam (PF08393) Pfam (PF03028) Pfam (PF18198) Pfam (PF12774) Pfam (PF21499) Pfam (PF12775) Pfam (PF22597) Pfam (PF12780) Pfam (PF12777) Pfam (PF00959) Pfam (PF12781) In PDB | Saccharomyces cerevisiae (Baker's yeast) | |
| 2 | A | (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile | non-polymer | 481.7 | 2 | Chemie (ZG7) | |||
| 3 | A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
A: 1364 - 3119 (UniProt: P36022)
A: 3126 - 3285 (UniProt: P00720)
A: 3292 - 4092 (UniProt: P36022)
| PDB | External Database | Details |
|---|---|---|
| Gly 1363 | - | expression tag |
| Gln 1849 | Glu 1849 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 3136 | Arg 12 | conflict |
| Thr 3178 | Cys 54 | conflict |
| Ala 3221 | Cys 97 | conflict |
| Arg 3261 | Ile 137 | conflict |
| Gly 3286 | - | linker |
| Ser 3287 | - | linker |
| Gly 3288 | - | linker |
| Ser 3289 | - | linker |
| Gly 3290 | - | linker |
| Ser 3291 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 3120 | - | linker |
| Ser 3121 | - | linker |
| Gly 3122 | - | linker |
| Ser 3123 | - | linker |
| Gly 3124 | - | linker |
| Ser 3125 | - | linker |
| Asp 3742 | Asn 3742 | conflict |
| Val 3895 | Phe 3895 | conflict |
| Asp 4072 | Asn 4072 | conflict |
| Gly 4093 | - | expression tag |
| Ser 4094 | - | expression tag |
| Gly 4095 | - | expression tag |
| Ser 4096 | - | expression tag |
| Gly 4097 | - | expression tag |
| Ser 4098 | - | expression tag |
| His 4099 | - | expression tag |
| His 4100 | - | expression tag |
| His 4101 | - | expression tag |
| His 4102 | - | expression tag |
| His 4103 | - | expression tag |
| His 4104 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 304889.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1494.9 | |
| All* | Total formula weight | 306384.8 |
