7MGX
Structure of EmrE-D3 mutant in complex with monobody L10 and methyl viologen
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, E, B, F) | Multidrug transporter EmrE | polymer | 110 | 11907.3 | 4 | UniProt (P23895) Pfam (PF00893) | Escherichia coli | Efflux-multidrug resistance protein EmrE,Ethidium resistance protein,Methyl viologen resistance protein C |
| 2 | B, D, F, H (C, G, D, H) | L10 Monobody | polymer | 91 | 9931.9 | 4 | Homo sapiens | ||
| 3 | I, J (A, E) | 1,1'-dimethyl-4,4'-bipyridin-1-ium | non-polymer | 186.3 | 2 | Chemie (KHJ) |
Sequence modifications
A, E, B, F: 1 - 110 (UniProt: P23895)
| PDB | External Database | Details |
|---|---|---|
| Asn 25 | Glu 25 | engineered mutation |
| Ile 31 | Trp 31 | engineered mutation |
| Met 34 | Val 34 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 87356.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 372.5 | |
| All* | Total formula weight | 87729.4 |
