7MGJ
TNNI3K complexed with N-methyl-4-(4-(3-(3-(trifluoromethyl) phenyl) ureido) phenoxy)picolinamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Serine/threonine-protein kinase TNNI3K | polymer | 330 | 37163.9 | 4 | UniProt (Q59H18) Pfam (PF07714) In PDB | Homo sapiens (Human) | Cardiac ankyrin repeat kinase,Cardiac troponin I-interacting kinase,TNNI3-interacting kinase |
| 2 | A, B, C, D | N-methyl-4-[4-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]pyridine-2-carboxamide | non-polymer | 430.4 | 4 | Chemie (ZFS) | |||
| 3 | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 402 - 730 (UniProt: Q59H18)
| PDB | External Database | Details |
|---|---|---|
| Gly 401 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 148655.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1721.5 | |
| All* | Total formula weight | 150376.9 |
