7MFP
crystal structure of the L136 aminotransferase K185A from acanthamoeba polyphaga mimivirus in the presence of the UDP-viosamine external aldimine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | L136 aminotransferase | polymer | 356 | 40230.7 | 4 | UniProt (Q5UPL1) Pfam (PF01041) | Acanthamoeba polyphaga mimivirus (APMV) | |
| 2 | E, I, N, S (A, B, C, D) | (2R,3R,4S,5S,6R)-3,4-dihydroxy-5-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-6-methyloxan-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen diphosphate (non-preferred name) | non-polymer | 778.4 | 4 | Chemie (Z7P) | |||
| 3 | F, G, J, K, O... (A, B, C, D) | CHLORIDE ION | non-polymer | 35.5 | 8 | Chemie (CL) | |||
| 4 | H, L, Q, V, W... (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | M, R (B, C) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | AA, BA, Y, Z (C, D, A, B) | water | water | 18.0 | 1354 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 352 (UniProt: Q5UPL1)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 185 | Lys 185 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 160922.6 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 3815.8 | |
| All* | Total formula weight | 164738.4 |
