7MDA
Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103A mutant co-crystallized with NL1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | H | Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase | polymer | 380 | 41417.6 | 1 | UniProt (X5E0F1) Pfam (PF01053) UniProt (by SIFTS) (A0A0H3K724) In PDB | Staphylococcus aureus | Cystathionine beta-lyase,Cystathionine gamma-lyase,Cystathionine gamma-synthase |
| 2 | H | N-[(6-bromo-1H-indol-1-yl)acetyl]glycine | non-polymer | 311.1 | 2 | Chemie (LB6) | |||
| 3 | H | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | H | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 5 | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
H: 2 - 380 (UniProt: X5E0F1)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Ala 103 | Tyr 103 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41417.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 906.5 | |
| All* | Total formula weight | 42324.2 |
