7MD8
Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103N mutant co-crystallized with NL2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase | polymer | 380 | 41460.6 | 1 | UniProt (X5E0F1) Pfam (PF01053) UniProt (by SIFTS) (A0A0H3K724) | Staphylococcus aureus | Cystathionine beta-lyase,Cystathionine gamma-lyase,Cystathionine gamma-synthase |
| 2 | B (H) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 3 | C, D (H) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | E, F, G, H, J (H) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | I (H) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 6 | K (H) | water | water | 18.0 | 260 | Chemie (HOH) |
Sequence modifications
H: 2 - 380 (UniProt: X5E0F1)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Asn 103 | Tyr 103 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41460.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 991.9 | |
| All* | Total formula weight | 42452.5 |
