7MBI
Structure of SARS-CoV2 3CL protease covalently bound to peptidomimetic inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | 3C-like proteinase | polymer | 306 | 33825.5 | 4 | UniProt (P0DTD1) Pfam (PF05409) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
| 2 | A, B, C, D | 4-methoxy-N-[(2S)-4-methyl-1-oxo-1-({(2S)-3-oxo-1-[(3S)-2-oxopiperidin-3-yl]butan-2-yl}amino)pentan-2-yl]-1H-indole-2-carboxamide | non-polymer | 470.6 | 4 | Chemie (YWJ) | |||
| 3 | B | 2,4,6-trimethylpyridine-3-carboxylic acid | non-polymer | 165.2 | 1 | Chemie (FN7) | |||
| 4 | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 135302.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2047.4 | |
| All* | Total formula weight | 137349.6 |
