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SARS-CoV-2 Main Protease (Mpro) C145A in Complex with Cleavage Site Nsp8/9 (P6-P1)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, B, D3C-like proteinasepolymer30633793.54UniProt (P0DTD1)
Pfam (PF05409)
In PDB
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase
2E, G, F, HSER-ALA-VAL-LYS-LEU-GLNpolymer6645.84UniProt (P0DTD1)
In PDB
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)
3waterwater18.01622Chemie (HOH)
Sequence modifications
A, C, B, D: 1 - 306 (UniProt: P0DTD1)
PDBExternal DatabaseDetails
Ala 145Cys 3408engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight137757.0
All*Total formula weight137757.0
*Water molecules are not included.

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PDB entries from 2024-10-09

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