7MB8
SARS-CoV-2 Main Protease (Mpro) C145A in Complex with Cleavage Site Nsp8/9 (P6-P1)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, B, D | 3C-like proteinase | polymer | 306 | 33793.5 | 4 | UniProt (P0DTD1) Pfam (PF05409) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
2 | E, G, F, H | SER-ALA-VAL-LYS-LEU-GLN | polymer | 6 | 645.8 | 4 | UniProt (P0DTD1) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
3 | water | water | 18.0 | 1622 | Chemie (HOH) |
Sequence modifications
A, C, B, D: 1 - 306 (UniProt: P0DTD1)
PDB | External Database | Details |
---|---|---|
Ala 145 | Cys 3408 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 137757.0 | |
All* | Total formula weight | 137757.0 |