7MB4
SARS-CoV-2 Main Protease (Mpro) C145A in Complex with Cleavage Site Nsp4/5 (P6-P1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, D, C, B) | 3C-like proteinase | polymer | 306 | 33793.5 | 4 | UniProt (P0DTD1) Pfam (PF05409) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
| 2 | E, F, G, H (E, H, G, F) | THR-SER-ALA-VAL-LEU-GLN | polymer | 6 | 617.7 | 4 | UniProt (P0DTD1) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | nsp4 |
| 3 | I, J, K, L, M... (A, D, C, B, E...) | water | water | 18.0 | 1098 | Chemie (HOH) |
Sequence modifications
A, D, C, B: 1 - 306 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ala 145 | Cys 3408 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 137644.7 | |
| All* | Total formula weight | 137644.7 |
