7MB3

SARS-CoV-2 Main Protease (Mpro) in Complex with Covalent Inhibitor SM145

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, D, C, B, E...)	3C-like proteinase	polymer	306	33825.5	6	UniProt (P0DTD1) Pfam (PF05409)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)	3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase
2	G, H, I, J, K... (A, D, C, B, E...)	N-{3-[(prop-2-yn-1-yl)oxy]propanoyl}-D-phenylalanyl-N-{(2R)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pentan-2-yl}-L-phenylalaninamide	non-polymer		632.7	6	Chemie (YVV)
3	M, N, O, P, Q... (A, D, C, B, E...)	water	water		18.0	1008	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	202953.3
Non-Polymers*	Number of molecules	6
	Total formula weight	3796.5
All*	Total formula weight	206749.8

*Water molecules are not included.