7MAN
HIV-1 Protease (I84V) in Complex with PU9 (LR2-80)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Protease | polymer | 99 | 10817.8 | 2 | UniProt (P03367) Pfam (PF00077) UniProt (by SIFTS) (P12497) | Human immunodeficiency virus 1 (HIV-1) | PR,Retropepsin |
| 2 | C, D, E, F (B, A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | G (A) | diethyl [(4-{(2S,3R)-4-{[(2H-1,3-benzodioxol-5-yl)sulfonyl](2-ethylbutyl)amino}-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxybutyl}phenoxy)methyl]phosphonate | non-polymer | 770.8 | 1 | Chemie (XW4) | |||
| 4 | H, I (B, A) | water | water | 18.0 | 231 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 99 (UniProt: P03367)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 507 | conflict |
| Asn 37 | Ser 537 | conflict |
| Val 84 | Ile 584 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21635.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1155.1 | |
| All* | Total formula weight | 22790.7 |
