7MAI
HIV-1 Protease (I84V) in Complex with PU5 (LR4-47)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, A | Protease | polymer | 99 | 10817.8 | 2 | UniProt (P03367) Pfam (PF00077) UniProt (by SIFTS) (P12497) In PDB | Human immunodeficiency virus 1 (HIV-1) | PR,Retropepsin |
| 2 | A | diethyl [(4-{(2S,3R)-4-{[(1,3-benzothiazol-6-yl)sulfonyl][(2S)-2-methylbutyl]amino}-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxybutyl}phenoxy)methyl]phosphonate | non-polymer | 769.9 | 1 | Chemie (XVJ) | |||
| 3 | water | water | 18.0 | 76 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 99 (UniProt: P03367)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 507 | conflict |
| Asn 37 | Ser 537 | conflict |
| Val 84 | Ile 584 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21635.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 769.9 | |
| All* | Total formula weight | 22405.5 |
