7M9W
HIV-1 Protease (I84V) in Complex with NR02-73
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | Protease | polymer | 99 | 10817.8 | 2 | UniProt (P03367) Pfam (PF00077) UniProt (by SIFTS) (P12497) In PDB | Human immunodeficiency virus 1 (HIV-1) | PR,Retropepsin |
2 | A | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(1S)-1-hydroxy-2,3-dihydro-1H-indene-5-sulfonyl][(2S)-2-methylbutyl]amino}-1-phenylbutan-2-yl]carbamate | non-polymer | 602.7 | 1 | Chemie (YUD) | |||
3 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
4 | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 99 (UniProt: P03367)
PDB | External Database | Details |
---|---|---|
Lys 7 | Gln 507 | conflict |
Asn 37 | Ser 537 | conflict |
Val 84 | Ile 584 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 21635.6 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 987.0 | |
All* | Total formula weight | 22622.6 |