7M9N
HIV-1 Protease (I84V) in Complex with LR3-68
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Protease | polymer | 99 | 10817.8 | 2 | UniProt (P03367) Pfam (PF00077) UniProt (by SIFTS) (P12497) | Human immunodeficiency virus 1 (HIV-1) | PR,Retropepsin |
| 2 | C, E, F (B, A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | D (A) | diethyl [(4-{(2S,3R)-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxy-4-[{4-[(1S)-1-hydroxyethyl]benzene-1-sulfonyl}(2-methylpropyl)amino]butyl}phenoxy)methyl]phosphonate | non-polymer | 742.8 | 1 | Chemie (YWM) | |||
| 4 | G, H (B, A) | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 99 (UniProt: P03367)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 507 | conflict |
| Asn 37 | Ser 537 | conflict |
| Val 84 | Ile 584 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21635.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1031.0 | |
| All* | Total formula weight | 22666.6 |
