7M8K
Cryo-EM structure of Brazil (P.1) SARS-CoV-2 spike glycoprotein variant in the prefusion state (1 RBD up)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Spike glycoprotein | polymer | 1257 | 139326.3 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
| 2 | D, E, F, G, H... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 11 | In PDB GlyTouCan (G42666HT) | |||
| 3 | B, C, A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 29 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 1208 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Phe 18 | Leu 18 | conflict |
| Asn 20 | Thr 20 | conflict |
| Ser 26 | Pro 26 | conflict |
| Tyr 138 | Asp 138 | conflict |
| Ser 190 | Arg 190 | conflict |
| Thr 417 | Lys 417 | conflict |
| Lys 484 | Glu 484 | conflict |
| Tyr 501 | Asn 501 | conflict |
| Gly 614 | Asp 614 | conflict |
| Tyr 655 | His 655 | conflict |
| Gly 682 | Arg 682 | conflict |
| Ser 683 | Arg 683 | conflict |
| Ser 685 | Arg 685 | conflict |
| Pro 986 | Lys 986 | conflict |
| Pro 987 | Val 987 | conflict |
| Ile 1027 | Thr 1027 | conflict |
| Gly 1209 | - | expression tag |
| Ser 1210 | - | expression tag |
| Gly 1211 | - | expression tag |
| Tyr 1212 | - | expression tag |
| Ile 1213 | - | expression tag |
| Pro 1214 | - | expression tag |
| Glu 1215 | - | expression tag |
| Ala 1216 | - | expression tag |
| Pro 1217 | - | expression tag |
| Arg 1218 | - | expression tag |
| Asp 1219 | - | expression tag |
| Gly 1220 | - | expression tag |
| Gln 1221 | - | expression tag |
| Ala 1222 | - | expression tag |
| Tyr 1223 | - | expression tag |
| Val 1224 | - | expression tag |
| Arg 1225 | - | expression tag |
| Lys 1226 | - | expression tag |
| Asp 1227 | - | expression tag |
| Gly 1228 | - | expression tag |
| Glu 1229 | - | expression tag |
| Trp 1230 | - | expression tag |
| Val 1231 | - | expression tag |
| Leu 1232 | - | expression tag |
| Leu 1233 | - | expression tag |
| Ser 1234 | - | expression tag |
| Thr 1235 | - | expression tag |
| Phe 1236 | - | expression tag |
| Leu 1237 | - | expression tag |
| Gly 1238 | - | expression tag |
| Arg 1239 | - | expression tag |
| Ser 1240 | - | expression tag |
| Leu 1241 | - | expression tag |
| Glu 1242 | - | expression tag |
| Val 1243 | - | expression tag |
| Leu 1244 | - | expression tag |
| Phe 1245 | - | expression tag |
| Gln 1246 | - | expression tag |
| Gly 1247 | - | expression tag |
| Pro 1248 | - | expression tag |
| Gly 1249 | - | expression tag |
| His 1250 | - | expression tag |
| His 1251 | - | expression tag |
| His 1252 | - | expression tag |
| His 1253 | - | expression tag |
| His 1254 | - | expression tag |
| His 1255 | - | expression tag |
| His 1256 | - | expression tag |
| His 1257 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 417978.9 | |
| Branched | Number of molecules | 11 |
| Total formula weight | 4668.4 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 6415.0 | |
| All* | Total formula weight | 429062.3 |
