7M86
Human DNA Pol eta S113A with dA-ended primer and dATP: in crystallo reaction for 140 s
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DNA polymerase eta | polymer | 435 | 48601.7 | 1 | UniProt (Q9Y253) Pfam (PF00817) Pfam (PF21704) Pfam (PF11799) In PDB | Homo sapiens (Human) | RAD30 homolog A,Xeroderma pigmentosum variant type protein |
2 | T | DNA (5'-D(*CP*AP*TP*TP*TP*TP*GP*AP*CP*GP*CP*T)-3') | polymer | 12 | 3628.4 | 1 | Homo sapiens | ||
3 | P | DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*AP*A)-3') | polymer | 9 | 2748.8 | 1 | Homo sapiens | ||
4 | A, P | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
5 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
6 | A | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 1 | Chemie (DTP) | |||
7 | A | DIPHOSPHATE | non-polymer | 173.9 | 1 | Chemie (DPO) | |||
8 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
9 | water | water | 18.0 | 492 | Chemie (HOH) |
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Pro -1 | - | expression tag |
His 0 | - | expression tag |
Ala 113 | Ser 113 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 54978.9 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1054.4 | |
All* | Total formula weight | 56033.3 |