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7M82

Human DNA Pol eta with dA-ended primer and dATP: in crystallo reaction for 300 s

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA polymerase etapolymer43548617.71UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
In PDB
Homo sapiens (Human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2TDNA (5'-D(*AP*TP*TP*TP*TP*GP*AP*CP*GP*CP*T)-3')polymer113339.21Homo sapiens
3PDNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*AP*A)-3')polymer92748.81Homo sapiens
4A, PMAGNESIUM IONnon-polymer24.33Chemie (MG)
5ACALCIUM IONnon-polymer40.11Chemie (CA)
6AGLYCEROLnon-polymer92.13Chemie (GOL)
7A2'-DEOXYADENOSINE 5'-TRIPHOSPHATEnon-polymer491.21Chemie (DTP)
8ADIPHOSPHATEnon-polymer173.91Chemie (DPO)
9waterwater18.0500Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54705.7
Non-Polymers*Number of molecules9
Total formula weight1054.4
All*Total formula weight55760.1
*Water molecules are not included.

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PDB entries from 2024-07-24

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