7M7W
Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, L | Monoclonal antibody S2X259 Fab light chain | polymer | 219 | 22993.3 | 2 | Homo sapiens (Human) | ||
2 | A, H | Monoclonal antibody S2X259 Fab heavy chain | polymer | 229 | 24351.4 | 2 | Homo sapiens (Human) | ||
3 | D, F | Monoclonal antibody S2H97 Fab light chain | polymer | 218 | 22935.2 | 2 | Homo sapiens (Human) | ||
4 | C, E | Monoclonal antibody S2H97 Fab heavy chain | polymer | 223 | 24174.1 | 2 | Homo sapiens (Human) | ||
5 | S, R | Spike protein S1 | polymer | 216 | 24442.3 | 2 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
6 | S, R | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
7 | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence modifications
S, R: 328 - 531 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Glu 324 | - | expression tag |
Thr 325 | - | expression tag |
Gly 326 | - | expression tag |
Thr 327 | - | expression tag |
His 532 | - | expression tag |
His 533 | - | expression tag |
His 534 | - | expression tag |
His 535 | - | expression tag |
His 536 | - | expression tag |
His 537 | - | expression tag |
His 538 | - | expression tag |
His 539 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 237792.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 442.4 | |
All* | Total formula weight | 238235.2 |