7M7I
6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2 (TE-free)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, A | EryAI | polymer | 1593 | 167782.8 | 2 | UniProt (Q5UNP6) Pfam (PF00109) Pfam (PF02801) Pfam (PF16197) Pfam (PF00698) Pfam (PF08659) Pfam (PF00550) UniProt (by SIFTS) (Q03131) In PDB | Saccharopolyspora erythraea (Streptomyces erythraeus) | DEBS (3)M1(2) |
| 2 | C, E | 1B2 (light chain) | polymer | 249 | 26447.6 | 2 | Saccharopolyspora erythraea (Streptomyces erythraeus) | ||
| 3 | D, F | 1B2 (heavy chain) | polymer | 236 | 25715.8 | 2 | Homo sapiens (Human) | ||
| 4 | B | N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-(2-sulfanylethyl)-beta-alaninamide | non-polymer | 358.3 | 1 | Chemie (PN7) |
Sequence modifications
B, A: 32 - 1485 (UniProt: Q5UNP6)
B, A: 1491 - 1573 (UniProt: Q5UNP6)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Ala 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Thr 4 | - | expression tag |
| Asp 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Glu 7 | - | expression tag |
| Lys 8 | - | expression tag |
| Val 9 | - | expression tag |
| Ala 10 | - | expression tag |
| Glu 11 | - | expression tag |
| Tyr 12 | - | expression tag |
| Leu 13 | - | expression tag |
| Arg 14 | - | expression tag |
| Arg 15 | - | expression tag |
| Ala 16 | - | expression tag |
| Thr 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Asp 19 | - | expression tag |
| Leu 20 | - | expression tag |
| Arg 21 | - | expression tag |
| Ala 22 | - | expression tag |
| Ala 23 | - | expression tag |
| Arg 24 | - | expression tag |
| Gln 25 | - | expression tag |
| Arg 26 | - | expression tag |
| Ile 27 | - | expression tag |
| Arg 28 | - | expression tag |
| Glu 29 | - | expression tag |
| Leu 30 | - | expression tag |
| Glu 31 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Thr 1486 | - | linker |
| Ser 1487 | - | linker |
| Glu 1488 | - | linker |
| Leu 1489 | - | linker |
| Gly 1490 | - | linker |
| Pro 1574 | - | expression tag |
| Asn 1575 | - | expression tag |
| Ser 1576 | - | expression tag |
| Ser 1577 | - | expression tag |
| Ser 1578 | - | expression tag |
| Val 1579 | - | expression tag |
| Asp 1580 | - | expression tag |
| Lys 1581 | - | expression tag |
| Leu 1582 | - | expression tag |
| Ala 1583 | - | expression tag |
| Ala 1584 | - | expression tag |
| Ala 1585 | - | expression tag |
| Leu 1586 | - | expression tag |
| Glu 1587 | - | expression tag |
| His 1588 | - | expression tag |
| His 1589 | - | expression tag |
| His 1590 | - | expression tag |
| His 1591 | - | expression tag |
| His 1592 | - | expression tag |
| His 1593 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 439892.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 358.3 | |
| All* | Total formula weight | 440250.7 |
