7M63
Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with IACS-70099
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Indoleamine 2,3-dioxygenase 1 | polymer | 411 | 46295.3 | 2 | UniProt (P14902) Pfam (PF01231) In PDB | Homo sapiens (Human) | IDO-1,Indoleamine-pyrrole 2,3-dioxygenase |
2 | A, B | (2R)-N-(4-chlorophenyl)-2-[(1R,3S,5S,6r)-3-(5,6-difluoro-1H-benzimidazol-1-yl)bicyclo[3.1.0]hexan-6-yl]propanamide | non-polymer | 415.9 | 2 | Chemie (YRP) |
Sequence modifications
A, B: 11 - 403 (UniProt: P14902)
PDB | External Database | Details |
---|---|---|
Met -7 | - | initiating methionine |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
Ser 0 | - | expression tag |
Ser 1 | - | expression tag |
Gly 2 | - | expression tag |
Leu 3 | - | expression tag |
Val 4 | - | expression tag |
Pro 5 | - | expression tag |
Arg 6 | - | expression tag |
Gly 7 | - | expression tag |
Ser 8 | - | expression tag |
His 9 | - | expression tag |
Met 10 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 92590.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 831.7 | |
All* | Total formula weight | 93422.2 |