7M5E
MERS-CoV S bound to the broadly neutralizing B6 Fab fragment (C3 refinement)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, C, E) | Spike glycoprotein | polymer | 1359 | 149172.1 | 3 | UniProt (A0A140AYW5) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) UniProt (by SIFTS) (K9N5Q8) | Middle East respiratory syndrome-related coronavirus | |
| 2 | BA, D, H, N, R... (b, B, H, N, R...) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 6 | In PDB GlyTouCan (G81315DD) | |||
| 3 | CA, DA, E, GA, I... (c, d, D, g, I...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 12 | In PDB GlyTouCan (G42666HT) | |||
| 4 | F, P, Z (F, P, Z) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 3 | In PDB GlyTouCan (G89619KY) | |||
| 5 | AA, G, Q (a, G, Q) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 6 | EA, FA, K, L, U... (e, f, K, L, U...) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 6 | In PDB GlyTouCan (G22768VO) | |||
| 7 | HA, QA, ZA (A, C, E) | FOLIC ACID | non-polymer | 441.4 | 3 | Chemie (FOL) | |||
| 8 | AB, BB, CB, DB, EB... (E, A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 21 | Chemie (NAG) | |||
| 9 | HB, PA, YA (E, A, C) | N-acetyl-alpha-neuraminic acid | non-polymer | 309.3 | 3 | Chemie (SIA) |
Sequence modifications
A, C, E: 19 - 1294 (UniProt: A0A140AYW5)
| PDB | External Database | Details |
|---|---|---|
| Met -13 | - | initiating methionine |
| Gly -12 | - | expression tag |
| Ile -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Pro -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Pro -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Met -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Leu 1 | - | expression tag |
| Val 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Val 7 | - | expression tag |
| Leu 8 | - | expression tag |
| Leu 9 | - | expression tag |
| Met 10 | - | expression tag |
| Gly 11 | - | expression tag |
| Cys 12 | - | expression tag |
| Val 13 | - | expression tag |
| Ala 14 | - | expression tag |
| Glu 15 | - | expression tag |
| Thr 16 | - | expression tag |
| Gly 17 | - | expression tag |
| Thr 18 | - | expression tag |
| Ile 529 | Thr 529 | conflict |
| Ala 748 | Arg 748 | conflict |
| Gly 751 | Arg 751 | conflict |
| Gln 1020 | Arg 1020 | conflict |
| Pro 1060 | Val 1060 | conflict |
| Pro 1061 | Leu 1061 | conflict |
| Gly 1295 | - | expression tag |
| Ser 1296 | - | expression tag |
| Gly 1297 | - | expression tag |
| Arg 1298 | - | expression tag |
| Glu 1299 | - | expression tag |
| Asn 1300 | - | expression tag |
| Leu 1301 | - | expression tag |
| Tyr 1302 | - | expression tag |
| Phe 1303 | - | expression tag |
| Gln 1304 | - | expression tag |
| Gly 1305 | - | expression tag |
| Gly 1306 | - | expression tag |
| Gly 1307 | - | expression tag |
| Gly 1308 | - | expression tag |
| Ser 1309 | - | expression tag |
| Gly 1310 | - | expression tag |
| Tyr 1311 | - | expression tag |
| Ile 1312 | - | expression tag |
| Pro 1313 | - | expression tag |
| Glu 1314 | - | expression tag |
| Ala 1315 | - | expression tag |
| Pro 1316 | - | expression tag |
| Arg 1317 | - | expression tag |
| Asp 1318 | - | expression tag |
| Gly 1319 | - | expression tag |
| Gln 1320 | - | expression tag |
| Ala 1321 | - | expression tag |
| Tyr 1322 | - | expression tag |
| Val 1323 | - | expression tag |
| Arg 1324 | - | expression tag |
| Lys 1325 | - | expression tag |
| Asp 1326 | - | expression tag |
| Gly 1327 | - | expression tag |
| Glu 1328 | - | expression tag |
| Trp 1329 | - | expression tag |
| Val 1330 | - | expression tag |
| Leu 1331 | - | expression tag |
| Leu 1332 | - | expression tag |
| Ser 1333 | - | expression tag |
| Thr 1334 | - | expression tag |
| Phe 1335 | - | expression tag |
| Leu 1336 | - | expression tag |
| Gly 1337 | - | expression tag |
| His 1338 | - | expression tag |
| His 1339 | - | expression tag |
| His 1340 | - | expression tag |
| His 1341 | - | expression tag |
| His 1342 | - | expression tag |
| His 1343 | - | expression tag |
| His 1344 | - | expression tag |
| His 1345 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 447516.2 | |
| Branched | Number of molecules | 30 |
| Total formula weight | 20514.8 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 6897.4 | |
| All* | Total formula weight | 474928.3 |
