7M20

18-mer HeLa-tubulin rings in complex with Cryptophycin 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, D, F, H, J...	Tubulin beta-3 chain	polymer	450	50481.5	9	UniProt (Q13509) Pfam (PF00091) Pfam (PF03953) In PDB	Homo sapiens (Human)	Tubulin beta-4 chain,Tubulin beta-III
2	A, C, E, G, I...	Tubulin alpha-1B chain	polymer	451	50204.4	9	UniProt (P68363) Pfam (PF00091) Pfam (PF03953) In PDB	Homo sapiens (Human)	Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
3	H, J, L, N, P...	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	9	Chemie (GDP)
4	G, I, K, M, O...	Cryptophycin 1	non-polymer		655.2	9	Chemie (YNP)
5	E, G, I, K, M...	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	9	Chemie (GTP)

Contents of the asymmetric unit

Polymers	Number of chains	18
	Total formula weight	906173.7
Non-Polymers*	Number of molecules	27
	Total formula weight	14594.0
All*	Total formula weight	920767.7

*Water molecules are not included.