7M17
SN-407-LRRC8A in MSP1E3D1 lipid nanodiscs (Pose-1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Volume-regulated anion channel subunit LRRC8A | polymer | 819 | 95257.5 | 6 | UniProt (Q80WG5) Pfam (PF12534) Pfam (PF13855) | Mus musculus (Mouse) | Leucine-rich repeat-containing protein 8A |
| 2 | G, H, I, J, K... (A, B, C, D, E...) | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine | non-polymer | 744.0 | 18 | Chemie (PEE) | |||
| 3 | N (C) | 7-{[(2S)-2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl]oxy}heptanoic acid | non-polymer | 469.4 | 1 | Chemie (YNJ) |
Sequence modifications
A, B, C, D, E, F: 1 - 810 (UniProt: Q80WG5)
| PDB | External Database | Details |
|---|---|---|
| Ser 811 | - | expression tag |
| Asn 812 | - | expression tag |
| Ser 813 | - | expression tag |
| Leu 814 | - | expression tag |
| Glu 815 | - | expression tag |
| Val 816 | - | expression tag |
| Leu 817 | - | expression tag |
| Phe 818 | - | expression tag |
| Gln 819 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 571545.0 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 13862.1 | |
| All* | Total formula weight | 585407.1 |
