7M0N
The crystal structure of wild type PA endonuclease (A/Vietnam/1203/2004) in complex with Raltegravir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Protein PA-X | polymer | 187 | 21916.0 | 4 | UniProt (C6Y633) Pfam (PF00603) | Influenza A virus (A/ruddy turnstone/New Jersey/Sg-00524/2008(H4N6)) | |
| 2 | E, J, Q, V (A, B, C, D) | N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(1-methyl-1-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}ethyl)-6-oxo-1,6-di hydropyrimidine-4-carboxamide | non-polymer | 444.4 | 4 | Chemie (RLT) | |||
| 3 | AA, F, G, M, N... (D, A, B, C) | MANGANESE (II) ION | non-polymer | 54.9 | 8 | Chemie (MN) | |||
| 4 | BA, CA, H, I, O... (D, A, B, C) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 5 | K, L, W, X, Y (B, D) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 6 | DA, EA, FA, GA (A, B, C, D) | water | water | 18.0 | 189 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 50 (UniProt: C6Y633)
A, B, C, D: 73 - 196 (UniProt: C6Y633)
A, B, C, D: 73 - 196 (UniProt: C6Y633)
| PDB | External Database | Details |
|---|---|---|
| Gly 50 | - | linker |
| Gly 50 | - | linker |
| Ser 50 | - | linker |
| Thr 129 | Ile 129 | conflict |
| Glu 142 | Lys 142 | conflict |
| Ala 197 | - | expression tag |
| Ala 198 | - | expression tag |
| Ala 199 | - | expression tag |
| Glu 200 | - | expression tag |
| Leu 201 | - | expression tag |
| Ala 202 | - | expression tag |
| Leu 203 | - | expression tag |
| Val 204 | - | expression tag |
| Pro 205 | - | expression tag |
| Arg 206 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 87663.8 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 3446.1 | |
| All* | Total formula weight | 91110.0 |
