7LXM
Cryo-EM structure of ConM SOSIP.v7 (ConM) in complex with bNAb PGT122
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (A, C, E) | HIV-1 Env glycoprotein gp120 | polymer | 493 | 55897.9 | 3 | Human immunodeficiency virus 1 | ||
| 2 | B, F, J (B, D, F) | HIV-1 Env glycoprotein gp41 | polymer | 153 | 17214.5 | 3 | Human immunodeficiency virus 1 | ||
| 3 | C, G, K (H, N, P) | PGT122 Fab heavy chain | polymer | 235 | 25434.7 | 3 | Homo sapiens | ||
| 4 | D, H, L (L, M, O) | PGT122 Fab light chain | polymer | 213 | 22880.3 | 3 | Homo sapiens | ||
| 5 | AA, M, OA (a, G, o) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 3 | In PDB GlyTouCan (G94734OT) | |||
| 6 | AB, BA, BB, CA, DA... (0, b, 1, c, d...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 24 | In PDB GlyTouCan (G42666HT) | |||
| 7 | GA, S, UA (g, S, u) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 3 | In PDB GlyTouCan (G23799GS) | |||
| 8 | IA, U, WA (i, U, w) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G22573RC) | |||
| 9 | JA, V, XA (j, V, x) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1559.4 | 3 | In PDB GlyTouCan (G68668TB) | |||
| 10 | KA, LA, W, X, YA... (k, l, W, X, y...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 6 | In PDB GlyTouCan (G15407YE) | |||
| 11 | CB, DB, EB, FB, GB... (A, B, C, D, E...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 364281.9 | |
| Branched | Number of molecules | 42 |
| Total formula weight | 28526.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1990.9 | |
| All* | Total formula weight | 394798.9 |
