7LXI

Crystal structure of S-adenosylmethionine-dependent methyltransferase UmaA from Mycobacterium tuberculosis in complex with SAH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	S-adenosylmethionine-dependent methyltransferase UmaA	polymer	294	34162.7	1	UniProt (Q6MX39) Pfam (PF02353)	Mycobacterium tuberculosis	SAM-dependent methyltransferase UmaA
2	B (A)	HEXAETHYLENE GLYCOL	non-polymer		282.3	1	Chemie (P6G)
3	C, F (A)	NITRATE ION	non-polymer		62.0	2	Chemie (NO3)
4	D (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
5	E (A)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
6	G (A)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH)
7	H (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
8	I (A)	water	water		18.0	186	Chemie (HOH)

Sequence modifications

A: 1 - 286 (UniProt: Q6MX39)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34162.7
Non-Polymers*	Number of molecules	7
	Total formula weight	983.2
All*	Total formula weight	35146.0

*Water molecules are not included.