7LX3

Cryo-EM structure of EDC-crosslinked ConSOSL.UFO.664 (ConS-EDC) in complex with bNAb PGT122

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G (A, B, C)	Env glycoprotein gp160	polymer	658	73136.7	3		Human immunodeficiency virus 1
2	B, E, H (L, M, O)	PGT122 Fab light chain	polymer	213	22880.3	3		Homo sapiens
3	C, F, I (H, N, P)	PGT122 Fab heavy chain	polymer	235	25434.7	3		Homo sapiens
4	AA, BA, DA, EA, FA... (a, b, d, e, f...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	33	In PDB GlyTouCan (G42666HT)
5	CA, O, QA (c, J, q)	alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	3	In PDB GlyTouCan (G42984ZU)
6	HA, T, VA (h, T, v)	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1559.4	3	In PDB GlyTouCan (G68668TB)
7	KA, W, YA (k, W, y)	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	3	In PDB GlyTouCan (G56014GC)
8	AB, BB, CB, DB, EB... (A, B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	15	Chemie (NAG)

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	364355.1
Branched	Number of molecules	42
	Total formula weight	25121.2
Non-Polymers*	Number of molecules	15
	Total formula weight	3318.1
All*	Total formula weight	392794.4

*Water molecules are not included.