7LWH
Human neurofibromin 2/merlin residues 1-339 in complex with LATS1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Merlin | polymer | 339 | 40207.6 | 1 | UniProt (P35240) Pfam (PF09379) Pfam (PF00373) Pfam (PF09380) In PDB | Homo sapiens (Human) | Moesin-ezrin-radixin-like protein,Neurofibromin-2,Schwannomerlin,Schwannomin |
| 2 | B | Serine/threonine-protein kinase LATS1 | polymer | 23 | 2653.0 | 1 | UniProt (O95835) In PDB | Homo sapiens | Large tumor suppressor homolog 1,WARTS protein kinase,h-warts |
| 3 | A | IMIDAZOLE | non-polymer | 69.1 | 3 | Chemie (IMD) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 423 | Chemie (HOH) |
Sequence modifications
A: 1 - 339 (UniProt: P35240)
| PDB | External Database | Details |
|---|---|---|
| Val 190 | Ala 190 | conflict |
| Glu 302 | Gly 302 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42860.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 299.3 | |
| All* | Total formula weight | 43159.9 |
