7LUC
Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Fusion glycoprotein F0 | polymer | 527 | 58615.9 | 3 | UniProt (C3UPB8) Pfam (PF00523) | Respiratory syncytial virus | Fusion glycoprotein F1,Fusion glycoprotein F2 |
| 2 | D, F, H (D, F, H) | 01.4B Fab Heavy chain | polymer | 121 | 13154.8 | 3 | Homo sapiens (Human) | ||
| 3 | E, G, I (E, G, I) | 01.4B Fab Light chain | polymer | 112 | 12499.0 | 3 | Homo sapiens (Human) | ||
| 4 | J, L, N (J, L, N) | 32.4K Fab Heavy chain | polymer | 129 | 14140.8 | 3 | Homo sapiens (Human) | ||
| 5 | K, M, O (K, M, O) | 32.4K Fab Light chain | polymer | 107 | 11664.1 | 3 | Homo sapiens (Human) |
Sequence modifications
A, B, C: 26 - 513 (UniProt: C3UPB8)
| PDB | External Database | Details |
|---|---|---|
| Glu 66 | Lys 66 | conflict |
| Ile 67 | Asn 67 | engineered mutation |
| Val 76 | Ile 76 | conflict |
| Pro 215 | Ser 215 | engineered mutation |
| Ser 514 | - | expression tag |
| Ala 515 | - | expression tag |
| Ile 516 | - | expression tag |
| Gly 517 | - | expression tag |
| Gly 518 | - | expression tag |
| Tyr 519 | - | expression tag |
| Ile 520 | - | expression tag |
| Pro 521 | - | expression tag |
| Glu 522 | - | expression tag |
| Ala 523 | - | expression tag |
| Pro 524 | - | expression tag |
| Arg 525 | - | expression tag |
| Asp 526 | - | expression tag |
| Gly 527 | - | expression tag |
| Gln 528 | - | expression tag |
| Ala 529 | - | expression tag |
| Tyr 530 | - | expression tag |
| Val 531 | - | expression tag |
| Arg 532 | - | expression tag |
| Lys 533 | - | expression tag |
| Asp 534 | - | expression tag |
| Gly 535 | - | expression tag |
| Glu 536 | - | expression tag |
| Trp 537 | - | expression tag |
| Val 538 | - | expression tag |
| Leu 539 | - | expression tag |
| Leu 540 | - | expression tag |
| Ser 541 | - | expression tag |
| Thr 542 | - | expression tag |
| Phe 543 | - | expression tag |
| Leu 544 | - | expression tag |
| Gly 545 | - | expression tag |
| Ser 546 | - | expression tag |
| Leu 547 | - | expression tag |
| Glu 548 | - | expression tag |
| Val 549 | - | expression tag |
| Leu 550 | - | expression tag |
| Phe 551 | - | expression tag |
| Gln 552 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 330223.8 | |
| All* | Total formula weight | 330223.8 |
