7LUC

Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Fusion glycoprotein F0	polymer	527	58615.9	3	UniProt (C3UPB8) Pfam (PF00523) In PDB	Respiratory syncytial virus	Fusion glycoprotein F1,Fusion glycoprotein F2
2	D, F, H	01.4B Fab Heavy chain	polymer	121	13154.8	3		Homo sapiens (Human)
3	E, G, I	01.4B Fab Light chain	polymer	112	12499.0	3		Homo sapiens (Human)
4	J, L, N	32.4K Fab Heavy chain	polymer	129	14140.8	3		Homo sapiens (Human)
5	K, M, O	32.4K Fab Light chain	polymer	107	11664.1	3		Homo sapiens (Human)

Sequence modifications

A, B, C: 26 - 513 (UniProt: C3UPB8)

PDB	External Database	Details
Glu 66	Lys 66	conflict
Ile 67	Asn 67	engineered mutation
Val 76	Ile 76	conflict
Pro 215	Ser 215	engineered mutation
Ser 514	-	expression tag
Ala 515	-	expression tag
Ile 516	-	expression tag
Gly 517	-	expression tag
Gly 518	-	expression tag
Tyr 519	-	expression tag
Ile 520	-	expression tag
Pro 521	-	expression tag
Glu 522	-	expression tag
Ala 523	-	expression tag
Pro 524	-	expression tag
Arg 525	-	expression tag
Asp 526	-	expression tag
Gly 527	-	expression tag
Gln 528	-	expression tag
Ala 529	-	expression tag
Tyr 530	-	expression tag
Val 531	-	expression tag
Arg 532	-	expression tag
Lys 533	-	expression tag
Asp 534	-	expression tag
Gly 535	-	expression tag
Glu 536	-	expression tag
Trp 537	-	expression tag
Val 538	-	expression tag
Leu 539	-	expression tag
Leu 540	-	expression tag
Ser 541	-	expression tag
Thr 542	-	expression tag
Phe 543	-	expression tag
Leu 544	-	expression tag
Gly 545	-	expression tag
Ser 546	-	expression tag
Leu 547	-	expression tag
Glu 548	-	expression tag
Val 549	-	expression tag
Leu 550	-	expression tag
Phe 551	-	expression tag
Gln 552	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	15
	Total formula weight	330223.8
All*	Total formula weight	330223.8

*Water molecules are not included.