7LTK
STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH AN INHIBITOR THAT LACKS A ZINC BINDING GROUP (COMPOUND 12)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Histone deacetylase 2 | polymer | 376 | 43062.0 | 3 | UniProt (Q92769) Pfam (PF00850) | Homo sapiens (Human) | HD2 |
| 2 | D, L, S (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | E, F, M, N, T... (A, B, C) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 4 | G, O, V (A, B, C) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 5 | H, I, J, P, Q... (A, B, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 6 | Chemie (PEG) | |||
| 6 | K, R, X (A, B, C) | N-{(1S)-1-[5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl]pentyl}-1-methylazetidine-3-carboxamide | non-polymer | 407.5 | 3 | Chemie (YEM) | |||
| 7 | AA, Y, Z (C, A, B) | water | water | 18.0 | 1032 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 129186.0 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 2473.1 | |
| All* | Total formula weight | 131659.0 |
