7LSE

Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Far Eastern Subtype)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H	T025 Fab Heavy Chain	polymer	232	24834.7	1		Homo sapiens
2	L	T025 Fab Light Chain	polymer	214	23425.0	1		Homo sapiens
3	E	Envelope protein E	polymer	118	13290.0	1	UniProt (P07720) Pfam (PF02832) In PDB	Tick-borne encephalitis virus Far Eastern subtype (SOFV Sofjin virus)
4	H	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5		water	water		18.0	202	Chemie (HOH)

Sequence modifications

E: 301 - 397 (UniProt: P07720)

PDB	External Database	Details
His 398	-	expression tag
His 399	-	expression tag
His 400	-	expression tag
His 401	-	expression tag
His 402	-	expression tag
His 403	-	expression tag
Gly 404	-	expression tag
Leu 405	-	expression tag
Asn 406	-	expression tag
Asp 407	-	expression tag
Ile 408	-	expression tag
Phe 409	-	expression tag
Glu 410	-	expression tag
Ala 411	-	expression tag
Gln 412	-	expression tag
Lys 413	-	expression tag
Ile 414	-	expression tag
Glu 415	-	expression tag
Trp 416	-	expression tag
His 417	-	expression tag
Glu 418	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	61549.7
Non-Polymers*	Number of molecules	1
	Total formula weight	92.1
All*	Total formula weight	61641.8

*Water molecules are not included.