7LQ7
Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV503 and COVA1-16
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E (A, B, E) | Spike protein S1 | polymer | 205 | 23104.9 | 3 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
| 2 | C, F, M (C, F, H) | CV503 heavy chain | polymer | 224 | 23544.4 | 3 | Homo sapiens | ||
| 3 | D, G, H (D, G, L) | CV503 light chain | polymer | 216 | 22714.0 | 3 | Homo sapiens | ||
| 4 | I, K, L (T, P, y) | COVA1-16 heavy chain | polymer | 232 | 25100.1 | 3 | Homo sapiens | ||
| 5 | J, N, O (U, Q, z) | COVA1-16 light chain | polymer | 214 | 23415.8 | 3 | Homo sapiens | ||
| 6 | P, Q, R (A, B, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
A, B, E: 333 - 530 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 531 | - | expression tag |
| His 532 | - | expression tag |
| His 533 | - | expression tag |
| His 534 | - | expression tag |
| His 535 | - | expression tag |
| His 536 | - | expression tag |
| His 537 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 353637.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 354301.0 |
