7LPB
Cryo-EM structure of full-length TRPV1 with capsaicin at 25 degrees Celsius
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Transient receptor potential cation channel subfamily V member 1 | polymer | 868 | 98719.8 | 4 | UniProt (O35433) Pfam (PF00023) Pfam (PF00520) | Rattus norvegicus (Rat) | TrpV1,Capsaicin receptor,Osm-9-like TRP channel 1,OTRPC1,Vanilloid receptor 1,Vanilloid receptor type 1-like |
| 2 | CA, E, H, L, O... (D, A, B, C) | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine | non-polymer | 760.1 | 8 | Chemie (LBN) | |||
| 3 | AA, BA, EA, F, G... (D, A, B, C) | [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | non-polymer | 718.0 | 12 | Chemie (6OU) | |||
| 4 | DA, I, P, W (D, A, B, C) | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol | non-polymer | 749.0 | 4 | Chemie (YFP) | |||
| 5 | FA, K, R, Y (D, A, B, C) | (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide | non-polymer | 305.4 | 4 | Chemie (4DY) |
Sequence modifications
A, B, C, D: 1 - 838 (UniProt: O35433)
| PDB | External Database | Details |
|---|---|---|
| Glu 839 | - | expression tag |
| Asn 840 | - | expression tag |
| Ser 841 | - | expression tag |
| Leu 842 | - | expression tag |
| Glu 843 | - | expression tag |
| Val 844 | - | expression tag |
| Leu 845 | - | expression tag |
| Phe 846 | - | expression tag |
| Gln 847 | - | expression tag |
| Gly 848 | - | expression tag |
| Pro 849 | - | expression tag |
| Asp 850 | - | expression tag |
| Tyr 851 | - | expression tag |
| Lys 852 | - | expression tag |
| Asp 853 | - | expression tag |
| Asp 854 | - | expression tag |
| Asp 855 | - | expression tag |
| Asp 856 | - | expression tag |
| Lys 857 | - | expression tag |
| Ala 858 | - | expression tag |
| His 859 | - | expression tag |
| His 860 | - | expression tag |
| His 861 | - | expression tag |
| His 862 | - | expression tag |
| His 863 | - | expression tag |
| His 864 | - | expression tag |
| His 865 | - | expression tag |
| His 866 | - | expression tag |
| His 867 | - | expression tag |
| His 868 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 394879.0 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 18914.2 | |
| All* | Total formula weight | 413793.3 |
